Description
SereneQ NAD+ 500mg
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every cell in the body. It sits at the centre of cellular energy metabolism — it is the electron carrier that shuttles reducing equivalents through the mitochondrial electron transport chain to produce ATP. It is also the substrate consumed by sirtuins (SIRT1–7) and PARP enzymes, which govern DNA repair, gene regulation and stress response. NAD+ levels decline measurably with age and in conditions including obesity and neurodegeneration, which is the research rationale for supplementation.
What the research covers
The most studied mechanisms involve sirtuin activation and PARP-mediated DNA repair. Animal studies using NAD+ precursors (NMN, NR) have demonstrated improvements in muscle function, metabolic health and lifespan in multiple model organisms. Direct NAD+ infusion work in humans has examined cognitive function, energy metabolism and fatigue in small pilot studies. David Sinclair’s group at Harvard has been the most prominent in positioning NAD+ biology as a central longevity pathway. The intravenous route bypasses the gut conversion steps required by oral precursors, which is the research rationale for the injectable format.
Where the evidence sits
Human trial data on injectable NAD+ specifically is limited — most published work uses oral precursors. Animal longevity data is consistent but has not translated cleanly to human trials yet. NAD+ is not licensed as a medicine. Supplied strictly as a laboratory research chemical.
The pen format
This is where SereneQ does things differently. Instead of lyophilised vials that need reconstituting and drawing up separately, the compound arrives pre-loaded in solution in a graduated injection pen with a dial and a dose window.
- 500mg NAD+ per pen in pre-loaded solution
- Graduated dial with dose window
- 300 units total per pen · approx 1.67mg NAD+ per unit
- 4 × sealed pen tips, 32G 0.23 × 4mm
- Store refrigerated at 2–8°C. Protect from light.
- Batch number, expiry and serial printed directly on the pen barrel
Handling and storage
- Store refrigerated at 2–8°C. Do not freeze.
- Keep in the outer carton, away from direct light.
- Short periods at room temperature during transit are expected and normal.
- Use a fresh sealed tip for each dispense. Dispose of tips in a sharps container.
- Expiry 12/2027 on sealed, correctly stored stock.
- Keep out of reach of children and animals.
What is in the box
- 1 × SereneQ pre-filled injection pen
- 4 × sealed pen tips, 32G 0.23 × 4mm
- Serialised, QR-coded retail carton
Supplied strictly as a laboratory research chemical. Not licensed as a medicine in the UK or anywhere else. Not for human or veterinary use. The research cited covers animal and in vitro work unless otherwise stated.





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