Description
SereneQ Tesamorelin
Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH) in which a trans-3-hexenoic acid group is conjugated to the N-terminus to increase stability. It stimulates the pituitary gland to produce growth hormone through the body’s own feedback loop rather than delivering exogenous GH. It is the only GHRH analogue to have completed Phase 3 trials and received FDA approval — for the specific indication of HIV-associated lipodystrophy (excess visceral fat accumulation linked to antiretroviral therapy), where it was approved as Egrifta.
What the research covers
The primary evidence base is the lipodystrophy trials, which showed significant reductions in visceral adipose tissue (VAT) measured by CT scan over 26 weeks, alongside improvements in triglycerides, non-HDL cholesterol and waist circumference. Research outside that specific indication has examined tesamorelin in healthy adults with abdominal adiposity, in cognitive function studies in older adults, and in GH-deficient populations. The GHRH mechanism preserves pulsatile GH secretion and the intact feedback loop — the pituitary can still respond to somatostatin — which is why its GH profile differs from direct exogenous somatropin.
Where the evidence sits
FDA-approved only for HIV-associated lipodystrophy. The compound here is not pharmaceutical Egrifta. Supplied strictly as a laboratory research chemical.
The pen format
This is where SereneQ does things differently. Instead of lyophilised vials that need reconstituting and drawing up separately, the compound arrives pre-loaded in solution in a graduated injection pen with a dial and a dose window.
- Tesamorelin (GHRH analogue) in pre-loaded solution
- Graduated dial with dose window
- 300 units total per pen
- 4 × sealed pen tips, 32G 0.23 × 4mm
- Store refrigerated at 2–8°C. Do not freeze.
- Batch number, expiry and serial printed directly on the pen barrel
Handling and storage
- Store refrigerated at 2–8°C. Do not freeze.
- Keep in the outer carton, away from direct light.
- Short periods at room temperature during transit are expected and normal.
- Use a fresh sealed tip for each dispense. Dispose of tips in a sharps container.
- Expiry 12/2027 on sealed, correctly stored stock.
- Keep out of reach of children and animals.
What is in the box
- 1 × SereneQ pre-filled injection pen
- 4 × sealed pen tips, 32G 0.23 × 4mm
- Serialised, QR-coded retail carton
Supplied strictly as a laboratory research chemical. Not licensed as a medicine in the UK or anywhere else. Not for human or veterinary use. The research cited covers animal and in vitro work unless otherwise stated.






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